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Follistim AQ Cartridge

Generic name: follicle stimulating hormoneFOL-ik-al-STIM-ue-lay-ting-HOR-mone ]
Brand names: Follistim AQ Cartridge, Gonal-F, Gonal-f RFF
Drug class: Gonadotropins

Medically reviewed by Drugs.com on Feb 4, 2025. Written by Cerner Multum.

What is Follistim AQ Cartridge?

Follistim AQ Cartridge is used to treat infertility in women who cannot ovulate. Follistim AQ Cartridge is not effective in women with primary ovarian failure (when the ovaries are unable to produce an egg).

Follistim AQ Cartridge is also used in men to stimulate sperm production. This medicine is not effective in men with primary testicular failure (when the testicles are unable to produce sperm).

Follistim AQ Cartridge is often used together with another medication called human chorionic gonadotropin (hCG).

Follistim AQ Cartridge may also be used for purposes not listed in this medication guide.

Follistim AQ Cartridge side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some women using this medicine develop ovarian hyperstimulation syndrome (OHSS), a potentially life-threatening condition. Stop using this medicine and call your doctor right away if you have symptoms of OHSS during or shortly after using Follistim AQ Cartridge:

Also call your doctor at once if you have:

Common side effects of Follistim AQ Cartridge may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not use Follistim AQ Cartridge if you have an untreated or uncontrolled endocrine disorder (thyroid, pituitary gland, or adrenal gland), heavy or abnormal vaginal bleeding that has not been checked by a doctor, an ovarian cyst, or cancer of the breast, ovary, uterus, testicle, hypothalamus, or pituitary gland.

Do not use this medicine if you are pregnant. You may need to have a negative pregnancy test before starting this treatment.

Before taking this medicine

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Follistim AQ Cartridge.

You should not use Follistim AQ Cartridge if you are allergic to it, or if you have:

Do not use this medicine if you are already pregnant. You may need to have a negative pregnancy test before starting this treatment. Tell your doctor right away if you become pregnant.

Tell your doctor if you have ever had:

Fertility treatment may increase your chance of having multiple births (twins, triplets, etc). These are high-risk pregnancies both for the mother and the babies. Talk to your doctor if you have concerns about this risk.

You should not breastfeed while using Follistim AQ Cartridge.

How should I use Follistim AQ Cartridge?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You must remain under the care of a doctor while using Follistim AQ Cartridge.

Follistim AQ Cartridge is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

You may need to mix Follistim AQ Cartridge with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy or has particles in it. Call your pharmacist for new medicine.

To get pregnant, you may need to have sex daily for several days in a row. The timing of sex and medication dosing is important for Follistim AQ Cartridge to work.

You will need frequent medical tests.

If you use this medicine to get pregnant, you may also need occasional ultrasound exams. Based on your blood work, you may need to stop having sex for a short time. Follow your doctor's instructions very carefully.

Storing this medicine unopened (not in use):

Storing this medicine opened (in use):

Take the medicine out of the refrigerator and allow it to reach room temperature before injecting your dose. Do not heat the medicine.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Follistim AQ Cartridge?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Follistim AQ Cartridge?

Other drugs may affect Follistim AQ Cartridge, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Does Follistim AQ Cartridge interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Follistim aq cartridge Biosimilars

Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.

Reference products

These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There are 6 for Follistim AQ Cartridge.

Follistim (follitropin beta) - Organon USA Inc., a subsidiary of Merck & Co., Inc.
Formulation type Strength
Single-Dose Vial 150 IU Discontinued, Voluntarily Revoked
Single-Dose Vial 75 IU Discontinued, Voluntarily Revoked
Follistim
Follistim AQ (follitropin beta) - Organon USA Inc., a subsidiary of Merck & Co., Inc.
Formulation type Strength
Single-Dose Vial 150 IU/0.5 mL Discontinued, Voluntarily Revoked
Single-Dose Vial 75 IU/0.5 mL Discontinued, Voluntarily Revoked

View Follistim AQ information in detail.

Follistim AQ Cartridge (follitropin beta) - Organon USA LLC, a subsidiary of Organon & Co.
Formulation type Strength
Multi-Dose Cartridge 175 IU/0.21 mL Discontinued
Multi-Dose Cartridge 300 IU/0.36 mL
Multi-Dose Cartridge 600 IU/0.72 mL
Multi-Dose Cartridge 900 IU/1.08 mL
Gonal-f (follitropin alfa) - EMD Serono, Inc.
Formulation type Strength
Ampule 150 IU Discontinued
Ampule 37.5 IU Discontinued
Ampule 75 IU Discontinued
Multi-Dose Vial 1,050 IU (600 IU/mL)
Multi-Dose Vial 450 IU (600 IU/mL)

View Gonal-f information in detail.

Gonal-f RFF (follitropin alfa) - EMD Serono, Inc.
Formulation type Strength
Single-Dose Vial 150 IU Discontinued
Single-Dose Vial 37.5 IU Discontinued
Single-Dose Vial 75 IU

View Gonal-f RFF information in detail.

Gonal-f RFF RediJect (follitropin alfa) - EMD Serono, Inc.
Formulation type Strength
Autoinjector 300 IU/0.5 mL
Autoinjector 450 IU/0.75 mL
Autoinjector 900 IU/1.5 mL

View Gonal-f RFF RediJect information in detail.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.